Supercritical Fluid Chromatography (SFC) in the pharmaceutical industry
Posted on February 26, 2013
By: Larry Miller, Principal Scientist
Amgen
Abstract Supercritical Fluid Chromatography (SFC) is a chromatographic technique used for small molecule analysis and purification. In SFC a carbon dioxide based mobile phase is utilised. The low viscosity and high diffusivity of carbon dioxide allows higher flowrates than HPLC. In addition the use...
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Related Topics and Keywords
achiral purifications, chromatographic, HPLC, solubility, Supercritical Fluid Chromatography (SFC)
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