Single-Use Down Scale Downstream Processing for Validation of Viral Saftey Measures

Introduction Mammalian cell cultures, since the development of the first biopharmaceutical, tissue plasminogen activator expressed in Chinese Hamster Ovary cells (CHO) for acute myocardial infarction and stroke, have become a unique tool to produce in large cGMP scale of 15.000 – 20.000L fully aut...

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