Pyrogen Testing in the 21st Century
Posted on March 1, 2017
Ingo Spreitzer, Deputy Head
Division Microbiology, Section 1/3 “Microbial Safety”, Paul-Ehrlich-Institut, Langen, Germany
Abstract The rabbit pyrogen test (RPT) was introduced into the British Pharmacopoeia in 1912, and 1942 into the United States Pharmacopeia. Since then both the predictive RPT and improved pharmaceutical manufacturing led to the safety level expected nowadays. Frequently the RPT has been replaced by ...
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Related Topics and Keywords
Bacterial Endotoxin test, BET, Ingo Spreitzer, MAT, Monocyte Activation Test, pyrogen, pyrogen testing, rabbit pyrogen test, rpt
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