Continuous Capture and Continuous Recovery – Novel Ideas for Product Recovery from Perfusion Process Using ATF
03rd February 2021 | 10:00 am EST | Dr. Kerstin Lange, Team Lead Process Technology and Innovation, Advanced Bioprocessing and And Andrew Falconbridge Vice President Process Technology and Innovation, Alvotech |BOOK FREE SEAT FOR THIS WEBINAR
Alvotech developed an intensified fed-batch process using a cell retention device for the production of a complex fusion protein. The process uses the novel technique of High Productivity Harvest (HPH), which involves a traditional FB process and a clarification process using a cell retention device. Implementing the new process resulted in higher vcd and viability, improved product quality, and a reduction of cost of manufacture compared to the conventional fed-batch process.
Presented by Dr. Kerstin Lange, Team Lead Process Technology and Innovation, Advanced Bioprocessing At Alvotech
Kerstin obtained her Diploma and PhD degree in Biochemical Engineering from the TU Dortmund University in Germany. She joined Alvotech in 2017 and has been actively contributing to the development of new upstream processes. Today she is the team lead in the Process Technology and Innovation group, heading the Advanced Bioprocessing team. The team focusses on the investigation of innovative processes, process intensification, and process optimization.
And Andrew Falconbridge Vice President Process Technology and Innovation, Alvotech
Over 30 years in the Biotechnology industry. Over that time worked in manufacturing and development of Vaccines, therapeutic/Diagnostic enzymes and Mabs. Started carreer at Wellcomes then at Genzyme as before moving to Alvotech where has been for 5 years developing Biosimlers as Director of Drug substance development and Now Vice President of Process Technology and Innovation, reposnsiable for driving new technologies and innovation within Alvotech for development and manufacturing
Inspiring advances in bioprocessing, Repligen is a technology leader in filtration, chromatography, systems, process analytics and Protein A ligand development for bioprocessing and gene therapy. Propelled by a culture of innovation and collaboration, and with a focus on cost and process efficiencies, our people and our technologies help address critical steps in the production of therapeutics, vaccines and diagnostics worldwide. Named one of the fastest growing biotech companies in the USA, Repligen is headquartered in Boston, MA with major manufacturing sites in Massachusetts, California, New Jersey, Sweden, and Germany.