Study of Pharmaceutical Drug-Excipient Interaction by FTIR and Raman Spectroscopy
Posted on June 16, 2015
By: Ming Huang, Research Investigator II
Robert Wethman, Senior Research Scientist
John Wasylyk, Principal Scientist
Bristol-Myers Squibb
Abstract FTIR and Raman spectroscopy has been used widely to study the molecular-level interaction between drug and excipient in pharmaceutical formulations. Excipients are added to the pharmaceutical formulation for a number of reasons including, to modify the rate of dissolution, to overcome conte...
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Related Topics and Keywords
Bristol-Myers Squibb, dissolution, drug molecules, Drug-Excipient Interaction, Excipient, excipients, formation of complexes, FTIR, hydrogen-bonding interactions, improve the stability, John Wasylyk, Ming Huang, molecular-level interaction, Raman spectra, Raman spectroscopy, Robert Wethman, uniformity challenges
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