NanoDSF – A Lean Technology to Test Thermal Stability of Vaccines
Posted on December 19, 2017
Marina Kirkitadze, Head of Biophysics and Conformation Unit at Biochemistry Platform, Analytical R&D
Kristen Kalbfleisch, Co-op Student in the Biochemistry Platform, Analytical R&D
Sanofi Pasteur Ltd.
Abstract Characterization of materials throughout the vaccine production manufacturing chain is essential to ensure the customer receives high quality, safe, and effective product. Vaccines may contain various components such as antigens, adjuvants, excipients, emulsifiers, etc. One of the key attri...
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A LEAN TECHNOLOGY TO TEST THERMAL STABILITY OF VACCINES, aromatic residues, bovine serum albumin), characterization, drug substances, dye-free method, intrinsic fluorescence, Kristen Kalbfleisch, Lean Technologies, lysozyme, manufacturing chain, Marina Kirkitadze, model proteins, monitoring thermal stability, nanoDSF, ovalbumin, protein-adjuvant interactions, proteins, purified protein antigens, Sanofi Pasteur Ltd., the mechanisms behind protein-adjuvant interactions, tryptophan, Vaccine Development, vaccine drug products, vaccine production
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