Leveraging the benefits offered by HME over traditional Processing Techniques to enhance the Solubility of the Drug.
Posted on November 12, 2012
By: Sanju Dhawan, Manager In The Integrated Product Development
Organisation; Raviraj Pillai, Vice President In The Integrated Product
Development Organisation; Ridhurkar Devendra Narayan Rao, Swati
Kumari, Neeraj Kaul, Deepak Kumar, T Krishnamurthy.
Dr. Reddy’s Laboratories
Introduction The extrusion process was invented by Joseph Brama for the manufacturing of lead pipes at the end of the eighteenth century. Subsequently in the mid-nineteenth century, it was used for wire insulation polymer coating process1. Since then, extrusion is a well established process in the p...
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Related Topics and Keywords
Differential Scanning Calorimetry (DSC), downstream, extrusion, Hot Melt Extrusion (HME), Plasticisers, polymers, Rheoscope, solubility
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