Host Cell Protein Characterisation and Mass Spectrometry Strategies
Posted on November 22, 2018
Chia-Yi Lillian Liu, Research Scientist (Proteomics)
Hwee Tong Tan, Associate Staff Scientist (Proteomics)
Xuezhi Bi, Group Leader (Proteomics) /Senior Scientist
Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR)
Summary Host cell proteins (HCPs) are process-related contaminants that are released to the cell culture supernatant due to secretion or lysis of host cells during the production of biologics. Due to the potential adverse effects of HCPs on the biotherapeutics stability, quality and efficacy, monito...
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Related Topics and Keywords
cell culture supernatant, Host Cell Protein Characterisation, Mass Spectrometry Strategies, Multi-analyte ELISA
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