Towards a lean Manufacturing: Implementing Single-Use Process Analytical Technologies (PAT) tools at the seed stage to simplify cell culture operations


24th May 2017 | 10AM ET | Dr Jose R. Vallejos of Medimmune/AstraZeneca |WATCH THIS FREE ON DEMAND WEBINAR

Single-Use Process Analytical Technologies (PAT) tools have a great potential to not only increase process understanding at the seed stage but also simplify cell culture operations. By utilizing PAT, the risk from bioburden or contamination can be significantly reduced and the overall operating efficiency increased. In fact, PAT also provides a data-driven platform to integrate Process Development and Manufacturing Operations that can mitigate risks associated with technology/process transfer.

 

Presentation by Dr Jose R. Vallejos of Medimmune/AstraZeneca

Microsoft Word - BioPharma Article Towards a lean ManufacturingSince 2014, Dr. Vallejos has been working for Medimmune/AstraZeneca Biologics Operations as a Cell Culture Manufacturing Scientist. At Medimmune he has been a subject matter expert to support tech transfers, authored Process Characterization Protocols to support BLA filing and supported design and start-up of a new cell culture facility.
After graduating in 2011, Dr Vallejos worked for DSM Nutritional Lipids where he led the Pilot Lab to support the algae oils Manufacturing Facility. Dr Vallejos received his Ph.D. in Chemical Engineering from the University of Maryland at Baltimore County (UMBC) where he worked under the supervision of Professor Dr. Govind Rao and Professor Dr. Antonio Moreira at the Center for Advanced Sensor Technology (CAST). Dr Vallejos specializes in Lean Manufacturing by implementing PAT tools. His research work has been published in peer-reviewed scientific journals and in the Reference Book Comprehensive Biotechnology, 2nd Edition (Published by Elsevier). Dr Vallejos is a Fulbright-awarded scientist and his major research contribution is in reducing the process information gap at the seed stage in the Biotech Process Development and Manufacturing settings.