Acoustic Wave Separation: How It Works – Pall Corporation


In this animated video, see how Acoustic Wave Separation technology works in full detail.

Acoustic Wave Separation technology enables the continuous removal of CHO cells and cell debris using a single-use acoustic chamber to achieve clarification of harvested cell culture fluid, ready for downstream processing. The acoustophoretic removal is intrinsically scalable and optimized for the clarification of high density CHO cell lines to provide a robust single-use primary clarification solution that delivers quality equivalent to centrifugation without the scaling, footprint and cleaning issues common with this solution. Acoustic Wave Separation technology avoids the volume limitations experienced by depth filtration solutions that lead to large footprint and buffer consumption or the need for process additives to enhance performance.

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